{"id":28528,"date":"2026-08-10T13:23:17","date_gmt":"2026-08-10T10:23:17","guid":{"rendered":"https:\/\/apellaser.ro\/product\/bruker-invispim-lattice-pro-light-sheet-microscope\/"},"modified":"2026-08-10T15:26:26","modified_gmt":"2026-08-10T12:26:26","slug":"bruker-invispim-lattice-pro-light-sheet-microscope","status":"publish","type":"product","link":"https:\/\/apellaser.ro\/en\/product\/bruker-invispim-lattice-pro-light-sheet-microscope\/","title":{"rendered":"Bruker InViSPIM Lattice Pro Light-Sheet Microscope"},"content":{"rendered":"

(I) Description:<\/strong><\/p>\n

The Bruker InVi SPIM Lattice Pro is an advanced inverted light-sheet fluorescence microscope engineered for high-resolution imaging of live and fixed biological specimens. Utilizing a spatial light modulator (SLM), the system generates a wide range of illumination beam patterns\u2014including lattice light sheets\u2014allowing the illumination to be optimized for different sample types and experimental applications. Its inverted optical architecture, featuring high-NA illumination and detection objectives together with a fully environmentally controlled imaging chamber, enables long-term imaging under physiological conditions while minimizing photobleaching and phototoxicity. The InVi SPIM Lattice Pro also supports advanced imaging modalities, including structured illumination microscopy (SIM), calcium imaging, fluorescence lifetime imaging microscopy (FLIM), fluorescence correlation spectroscopy (FCS), and photomanipulation, making it a versatile platform for cutting-edge life science research.<\/p>\n

(II) Features and benefits:<\/strong><\/p>\n

\u00b7 High-resolution imaging of live and fixed biological specimens
\n\u00b7 Programmable illumination using Spatial Light Modulator (SLM) technology
\n\u00b7 Multiple illumination beam patterns, including lattice light sheets, optimized for different sample types
\n\u00b7 High-NA illumination and detection optics for superior image quality and sensitivity
\n\u00b7 Gentle light-sheet illumination minimizes photobleaching and phototoxicity during long-term imaging
\n\u00b7 Fully environmentally controlled imaging chamber for stable physiological conditions
\n\u00b7 Supports advanced imaging modalities including SIM, FLIM, FCS, calcium imaging, and photomanipulation
\n\u00b7 Flexible platform for demanding live-cell imaging and advanced fluorescence microscopy applications<\/p>\n

(III) Technical Specifications:<\/strong><\/p>\n

\u00b7 Imaging Modality:<\/strong> Inverted Light-Sheet Fluorescence Microscopy (LSFM)
\n\u00b7 Illumination technology:<\/strong> Advanced Illumination Module (AIM) with integrated Spatial Light Modulator (SLM)
\n\u00b7 Beam patterns:<\/strong> Static Gaussian, Scanned Gaussian, Scanned Bessel, Optical Lattice, and user-defined beam profiles
\n\u00b7 Advanced imaging modes:<\/strong> Structured Illumination Microscopy (SIM), FLIM, FCS, calcium imaging, and optional photomanipulation
\n\u00b7 Illumination objective:<\/strong> Special Optics 28.6\u00d7 @ 0.7 NA water immersion objective
\n\u00b7 Detection objective: <\/strong>Nikon CFI Apo 25\u00d7 @ 1.1 NA water immersion objective with correction collar
\n\u00b7 Effective magnification:<\/strong> 31,3\u00d7 \u0219i 62,5\u00d7
\n\u00b7 Detection:<\/strong> Two sCMOS cameras each equipped with up to 10 filters split by two selectable dichroic mirrors.
\n\u00b7 Excitation lasers:<\/strong> Up to 6 laser lines with chromatic correction
\n\u00b7 Emission filters:<\/strong> Up to 20 selectable emission filters
\n\u00b7 Environmental control:<\/strong> Temperature (20\u201337 \u00b0C), CO\u2082, O\u2082\/N\u2082, and humidity control for long-term live-cell imaging
\n\u00b7 Software:<\/strong> Bruker LuxBundle for acquisition, image reconstruction, visualization, and analysis
\n\u00b7 Photomanipulation (optional):<\/strong> Compatible with the Photomanipulation (PM) module for FRAP, photoablation, optogenetics, and ROI-based stimulation<\/p>\n

(IV) Producer:<\/strong> Bruker<\/p>\n

(V) Aplications:<\/strong> Live-Cell Imaging, Developmental Biology, Cell Biology, Neuroscience, Organoid and 3D Cell Culture Research, Cancer Biology, Stem Cell Research, Calcium Imaging, Structured Illumination Microscopy (SIM), Fluorescence Lifetime Imaging (FLIM), Fluorescence Correlation Spectroscopy (FCS), Protein Dynamics and Cell Signaling , Photomanipulation and Optogenetics, Long-Term Live Imaging.<\/p>\n","protected":false},"excerpt":{"rendered":"

Resources:<\/strong><\/p>\n

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