MINFLUX 3D | Abberior Instruments

The MINFLUX platform offers an unprecedented array of imaging possibilities and allows you to resolve structures as small as a molecule, along all three dimensions. This unmatched resolution capability combined with unprecedented speeds reveals sample details never seen before. The MINFLUX is the world’s most powerful fluorescence microscope.

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“Features & Benefits:

MINFLUX is the most precise and most photon-efficient way of localizing fluorescent molecules. With its new MINFLUX system, abberior has produced the first commercial fluorescence microscope that can achieve localization precisions of 1-3 nm (3D) in biological samples on large fields of view (10 x 15 μm). MINFLUX imaging means getting the maximal localization information out of your sample.
MINFLUX tracks molecular movements at frequencies up to 10 kHz, resolving molecular motion every 100 μs. That’s 100 times faster than conventional camera-based methods. Of course, tracking works in all three dimensions, i.e. along x, y, and z. Due to the low number of photons required for each localization, single molecules can be monitored with unprecedented spatio-temporal resolution (e.g. 28.000 localizations each at 20 nm resolution).
MINFLUX is the fastest way to localize fluorescent molecules. With its revolutionary MINFLUX microscope, abberior is raising the bar for molecular tracking with world-record temporal resolution, opening new doors for life-scientists across all disciplines.

Technical Specifications:

more than 100 kHz line frequency: scan 100 times faster than any other method.
1 – 3 nm localization precision in 3D: resolve 100 times better than confocal microscopy.
100 µs time per localization: track fluorophores 100 times faster than with a camera.”